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Publikace Oddělení toxikogenomiky


Vědecké publikace 2015-2018

Campa D, Pastore M, Capurso G, Hackert T, Di Leo M, Izbicki JR, Khaw KT, Gioffreda D, Kupcinskas J, Pasquali C, Macinga P, Kaaks R, Stigliano S, Peeters PH, Key TJ, Talar-Wojnarowska R, Vodicka P, Valente R, Vashist YK, Salvia R, Papaconstantinou I, Shimizu Y, Valsuani C, Zambon CF, Gazouli M, Valantiene I, Niesen W, Mohelnikova-Duchonova B, Hara K, Soucek P, Malecka-Panas E, Bueno-De-Mesquita HB, Johnson T, Brenner H, Tavano F, Fogar P, Ito H, Sperti C, Butterbach K, Latiano A, Andriulli A, Cavestro GM, Busch ORC, Dijk F, Greenhalf W, Matsuo K, Lombardo C, Strobel O, König AK, Cuk K, Strothmann H, Katzke V, Cantore M, Mambrini A, Oliverius M, Pezzilli R, Landi S, Canzian F. Do pancreatic cancer and chronic pancreatitis share the same genetic risk factors? A PANcreatic Disease ReseArch (PANDoRA) consortium investigation. Int J Cancer. 2018;142(2):290-296.

Soucek P, Vrana D, Ueng YF, Wei S, Kozevnikovova R, Guengerich FP. Selective changes in cholesterol metabolite levels in plasma of breast cancer patients after tumor removal. Clin Chem Lab Med. 2018;56(3):e78-e81.

Klein AP, Wolpin BM, Risch HA, Stolzenberg-Solomon RZ, Mocci E, Zhang M, Canzian F, Childs EJ, Hoskins JW, Jermusyk A, Zhong J, Chen F, Albanes D, Andreotti G, Arslan AA, Babic A, Bamlet WR, Beane-Freeman L, Berndt SI, Blackford A, Borges M, Borgida A, Bracci PM, Brais L, Brennan P, Brenner H, Bueno-de-Mesquita B, Buring J, Campa D, Capurso G, Cavestro GM, Chaffee KG, Chung CC, Cleary S, Cotterchio M, Dijk F, Duell EJ, Foretova L, Fuchs C, Funel N, Gallinger S, M Gaziano JM, Gazouli M, Giles GG, Giovannucci E, Goggins M, Goodman GE, Goodman PJ, Hackert T, Haiman C, Hartge P, Hasan M, Hegyi P, Helzlsouer KJ, Herman J, Holcatova I, Holly EA, Hoover R, Hung RJ, Jacobs EJ, Jamroziak K, Janout V, Kaaks R, Khaw KT, Klein EA, Kogevinas M, Kooperberg C, Kulke MH, Kupcinskas J, Kurtz RJ, Laheru D, Landi S, Lawlor RT, Lee IM, LeMarchand L, Lu L, Malats N, Mambrini A, Mannisto S, Milne RL, Mohelníková-Duchoňová B, Neale RE, Neoptolemos JP, Oberg AL, Olson SH, Orlow I, Pasquali C, Patel AV, Peters U, Pezzilli R, Porta M, Real FX, Rothman N, Scelo G, Sesso HD, Severi G, Shu XO, Silverman D, Smith JP, Soucek P, Sund M, Talar-Wojnarowska R, Tavano F, Thornquist MD, Tobias GS, Van Den Eeden SK, Vashist Y, Visvanathan K, Vodicka P, Wactawski-Wende J, Wang Z, Wentzensen N, White E, Yu H, Yu K, Zeleniuch-Jacquotte A, Zheng W, Kraft P, Li D, Chanock S, Obazee O, Petersen GM, Amundadottir LT. Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. Nat Commun. 2018;9(1):556.

Vrana D, Hlavac V, Brynychova V, Vaclavikova R, Neoral C, Vrba J, Aujesky R, Matzenauer M, Melichar B, Soucek P. ABC transporters and their role in the neoadjuvant treatment of esophageal cancer. Int J Mol Sci. 2018;19(3): 868.

Lettlova S, Brynychova V, Blecha J, Vrana D, Vondrusova M, Soucek P, Truksa J. Mir-301a-3p suppresses estrogen signaling by directly inhibiting ESR1 in Erα positive breast cancer. Cell Physiol Biochem. 2018;46:2601-2615.

Holy P, Kloudova A, Soucek P. Importance of genetic background of oxysterol signaling in cancer. Biochimie 2018;153:109-138.

Dvorak P, Leupen S, Soucek P. Circulating and circular RNAs and the need for rationalization and synthesis of the research spiral. Adv Clin Exp Med. 2018; in press.

Zemanek T, Melichar B, Lovecek M, Soucek P, Mohelnikova-Duchonova B. Biomarkers and pathways of chemoresistance and chemosensitivity for personalized treatment of pancreatic adenocarcinoma. Pharmacogenomics 2018; in press.

Soucek P. Genetika. In: Nádory jícnu a žaludku (Ed Vrana D a kol.). vydal Farmakon Press spol. s.r.o., 2018, s. 99-103. Praha, Czech Republic. Monography in Czech.

Brynychova V, Hlavac V, Ehrlichova M, Vaclavikova R, Nemcova-Furstova V, Pecha V, Trnkova M, Mrhalova M, Kodet R, Vrana D, Gatek J, Bendova M, Vernerova Z, Kovar J, Soucek P. Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target. Clin Chem Lab Med 2017; 55(1):111-122.

Vrana D, Matzenauer M, Aujesky R, Vrba R, Neoral C, Melichar B, Souček P. Potential Predictive Role of MicroRNAs in the Neoadjuvant Treatment of Esophageal Cancer. Anticancer Res. 2017;37(2):403-412.

Mohelnikova-Duchonova B, Strouhal O, Hughes DJ, Holcatova I, Oliverius M, Kala Z, Campa D, Rizzato C, Canzian F, Pezzilli R, Talar-Wojnarowska R, Malecka-Panas E, Sperti C, Zambon CF, Pedrazzoli S, Fogar P, Milanetto AC, Capurso G, Delle Fave G, Valente R, Gazouli M, Malleo G, Lawlor RT, Strobel O, Hackert T, Giese N, Vodicka P, Vodickova L, Landi S, Tavano F, Gioffreda D, Piepoli A, Pazienza V, Mambrini A, Pedata M, Cantore M, Bambi F, Ermini S, Funel N, Soucek P. SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival. Sci Rep 2017; 7:43812.

Dvorak R, Pesta M, Soucek P. ABC gene expression profiles have clinical importance and possibly create new hallmark of cancer. Tumor Biol 2017;39(5):1010428317699800.

Kloudova A, Brynychova V, Vaclavikova R, Vrana D, Gatek J, Mrhalova M, Kodet R, Soucek P. Expression of oxysterol pathway genes in estrogen positive breast carcinomas. Clin Endocrinol. 2017;86(6):852-861.

Kloudova A, Guengerich FP, Soucek P. The role of oxysterols in human cancer. Trends Endocrinol Metab. 2017; 28(7): 485-496.

Cerovska E, Elsnerova K, Vaclavikova R, Soucek P. The role of membrane transporters in ovarian cancer chemoresistance and prognosis. Expert Opin Drug Metab Toxicol. 2017; 13(7): 741–753.

Dvorak P, Hlavac V, Mohelnikova-Duchonova B, Liska V, Pesta M, Soucek P. Downregulation of ABC Transporters in Non-neoplastic Tissues Confers Better Prognosis for Pancreatic and Colorectal Cancer Patients. J Cancer 2017; 8(11): 1959-1971.

Mohelnikova-Duchonova B, Kocik M, Duchonova B, Brynychova V, Oliverius M,Hlavsa J, Honsova E, Mazanec J, Kala Z, Ojima I, Hughes DJ, Doherty JE, Murray HA, Crockard MA, Lemstrova R, Soucek P. Hedgehog pathway overexpression in pancreatic cancer is abrogated by new generation taxoid SB-T-1216. Pharmacogenomics J 2017;17(5):452-460.

Soucek P. Xenobiotics. In: Encyclopedia of Cancer, Schwab M (Ed.), 4th ed., Springer-Verlag Berlin Heidelberg, 2017, pp. 1-5.

Wang C-W, Huang C-C, Chou P-H, Chang Y-P, Wei S, Guengerich FP, Chou Y-C, Wang S-F, Lai P-S, Souček P, Ueng Y-F. 7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic aktivity and mTOR pathway. Oncotarget. 2017; 8(39):66033-66050.

Lemstrova R, Brynychova V, Hughes DJ, Hlavac V, Dvorak P, Doherty JE, Murray HA, Crockard M, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Lovecek M, Havlik R, Ehrmann J, Strouhal O, Soucek P, Melichar B, Mohelnikova-Duchonova B. Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome. Oncol Lett. 2017; 14(5): 5980-5988.

Elsnerova K, Bartakova A, Tihlarik J, Bouda J, Rob L, Skapa P, Hruda M, Gut I, Mohelnikova-Duchonova B, Soucek P, Vaclavikova R. Gene Expression Profiling Reveals Novel Candidate Markers of Ovarian Carcinoma Intraperitoneal Metastasis. J Cancer. 2017;8(17):3598-3606.

Souček P: Význam genetických polymorfismů enzymů metabolizujících léčiva u nádorových onemocnění. In: Metabolismus léčiv a jiných xenobiotik 2. vydání, upravené a rozšířené (Ed. Skálová L. a kolektiv), vydalo Karolinum v Praze 2017, 172 stran, Monography in Czech.

Janatová M, Borecká M, Soukupová J, Kleiblová P, Stříbrná J, Vočka M, Zemánková P, Panczak A, Veselá K, Souček P, Foretová L, Kleibl Z. PALB2 as Another Candidate Gene for Genetic Testing in Patients with Hereditary Breast Cancer in Czech Republic. Klin Onkol. 2016;29 Suppl 1:S31-4. Czech.

Elsnerova K, Beatrice Mohelnikova-Duchonova B, Cerovska E, Ehrlichova M, Gut I, Rob L, Skapa P, Hruda M, Bartakova A, Bouda J, Vodicka P, Soucek P, Vaclavikova R. Gene expression of membrane transporters: importance for prognosis and progression of ovarian carcinoma. Oncol. Rep. 2016; 35: 2159-2170.

Borecka M, Zemankova P, Vocka M, Soucek P, Soukupova J, Kleiblova P, Sevcik J, Kleibl Z, Janatova M. Mutation analysis of the PALB2 gene in unselected pancreatic cancer patients in the Czech Republic. Cancer Genet. 2016;209(5):199-204.

Borecka M, Zemankova P, Lhota F, Soukupova J, Kleiblova P, Vocka M, Soucek P, Ticha I, Kleibl Z, Janatova M. The c.657del5 variant in the NBN gene predisposes to pancreatic cancer. Gene. 2016;587(2):169-172.

Brynychova V, Ehrlichova M, Hlavac V, Nemcova-Furstova V, Pecha V, Leva J, Trnkova M, Mrhalova M, Kodet R, Vrana D, Kovar J, Vaclavikova R, Gut I, Soucek P. Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients. Biomed Pharmacother 2016;83:857-864.

Krizkova V, Dubova M, Susova S, Vycital O, Bruha J, Skala M, Liska V, Daum O, Soucek P. Protein expression of ATP binding cassette transporters ABCC10 and ABCC11 associates with survival of colorectal cancer patients. Cancer Chemother Pharmacol. 2016; 78(3):595-603.

Lněničková K, Procházková E, Skálová L, Matoušková P, Bártíková H, Souček P, Szotáková B. Catechins Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells. Molecules 2016; 21: 1186.

Rizzato C, Campa D, Talar-Wojnarowska R, Halloran C, Kupcinskas J, Butturini G, Mohelníková-Duchoňová B, Sperti C, Tjaden C, Ghaneh P, Hackert T, Funel N, Giese N, Tavano F, Pezzilli R, Pedata M, Pasquali C, Gazouli M, Mambrini A, Souček P, di Sebastiano P, Capurso G, Cantore M, Oliverius M, Offringa R, Małecka-Panas E, Strobel O, Scarpa A, Canzian F. Association of genetic polymorphisms with survival of pancreatic ductal adenocarcinoma patients. Carcinogenesis. 2016; 37(10):957-964.

Němcová-Fürstová V, Kopperová D, Balušíková K, Ehrlichová M, Brynychová V, Václavíková R, Daniel P, Souček P, Kovář J. Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters. Toxicol Appl Pharmacol. 2016; 310:215-228.

Kunicka T, Prochazka P, Krus I, Bendova P, Protivova M, Susova S, Hlavac V, Liska V, Novak P, Schneiderova M, Pitule P, Bruha J, Vycital O, Vodicka P, Soucek P. Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma. BMC Cancer 2016;16(1):795.

Brynychova Vaclavikova R, Kubackova K, Mrhalova M, Kodet R, Rauš K, Vrana D, Gatek J, Bendova M, Soucek P. Clinical and Functional Importance of Selected CASP8 and CASP9 Polymorphisms in Breast Carcinoma. Klin Onkol 2016; 29(6):445-453.

Campa D, Pastore M, Gentiluomo M, Talar-Wojnarowska R, Kupcinskas J, Malecka-Panas E, Neoptolemos JP, Niesen W, Vodicka P, Delle Fave G, Bas Bueno-de-Mesquita H, Gazouli M, Pacetti P, Di Leo M, Ito H, Klüter H, Soucek P, Corbo V, Yamao K, Hosono S, Kaaks R, Vashist Y, Gioffreda D, Strobel O, Shimizu Y, Dijk F, Andriulli A, Ivanauskas A, Bugert P, Tavano F, Vodickova L, Federico Zambon C, Lovecek M, Landi S, Key TJ, Boggi U, Pezzilli R, Jamroziak K, Mohelnikova-Duchonova B, Mambrini A, Bambi F, Busch O, Pazienza V, Valente R, Theodoropoulos GE, Hackert T, Capurso G, Martina Cavestro G, Pasquali C, Basso D, Sperti C, Matsuo K, Büchler M, Khaw KT, Izbicki J, Costello E, Katzke V, Michalski C, Stepien A, Rizzato C, Canzian F. Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk. Oncotarget. 2016 7(35):57011-57020.

Zhang M, Wang Z, Obazee O, Jia J, Childs EJ, Hoskins J, Figlioli G, Mocci E, Collins I, Chung CC, Hautman C, Arslan AA, Beane-Freeman L, Bracci PM, Buring J, Duell EJ, Gallinger S, Giles GG, Goodman GE, Goodman PJ, Kamineni A, Kolonel LN, Kulke MH, Malats N, Olson SH, Sesso HD, Visvanathan K, White E, Zheng W, Abnet CC, Albanes D, Andreotti G, Brais L, Bueno-de-Mesquita HB, Basso D, Berndt SI, Boutron-Ruault MC, Bijlsma MF, Brenner H, Burdette L, Campa D, Caporaso NE, Capurso G, Cavestro GM, Cotterchio M, Costello E, Elena J, Boggi U, Gaziano JM, Gazouli M, Giovannucci EL, Goggins M, Gross M, Haiman CA, Hassan M, Helzlsouer KJ, Hu N, Hunter DJ, Iskierka-Jazdzewska E, Jenab M, Kaaks R, Key TJ, Khaw KT, Klein EA, Kogevinas M, Krogh V, Kupcinskas J, Kurtz RC, Landi MT, Landi S, Le Marchand L, Mambrini A, Mannisto S, Milne RL, Neale RE, Oberg AL, Panico S, Patel AV, Peeters PH, Peters U, Pezzilli R, Porta M, Purdue M, Quiros JR, Riboli E, Rothman N, Scarpa A, Scelo G, Shu XO, Silverman DT, Soucek P, Strobel O, Sund M, Małecka-Panas E, Taylor PR, Tavano F, Travis RC, Thornquist M, Tjønneland A, Tobias GS, Trichopoulos D, Vashist Y, Vodicka P, Wactawski-Wende J, Wentzensen N, Yu H, Yu K, Zeleniuch-Jacquotte A, Kooperberg C, Risch HA, Jacobs EJ, Li D, Fuchs C, Hoover R, Hartge P, Chanock SJ, Petersen GM, Stolzenberg-Solomon RS, Wolpin BM, Kraft P, Klein AP, Canzian F, Amundadottir LT. Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21. Oncotarget. 2016; 7(41):66328-66343.

Hlaváč V, Souček P. Role of family D ATP-binding cassette transporters (ABCD) in cancer. Biochem Soc Trans. 2015;43(5):937-42.

Soucek P, Hlavac V, Elsnerova K, Vaclavikova R, Kozevnikovova R, Raus K. Whole Exome Sequencing Analysis of ABCC8 and ABCD2 Genes Associating With Clinical Course of Breast Carcinoma. Physiol. Res. 2015; 64 (Suppl. 4): S549-S557.

Hemminki K, Frank C, Försti A, Musak L, Kazimirova A, Barancokova M, Horska A, Vymetalkova V, Smerhovsky Z, Naccarati A, Soucek P, Vodickova L, Buchancova J, Smolkova B, Dusinska M, Vodicka P. Metabolic gene variants associated with chromosomal aberrations in healthy humans. Genes Chromosomes Cancer. 2015;54(4):260-6.

Campa D, Rizzato C, Stolzenberg-Solomon R, Pacetti P, Vodicka P, Cleary SP, Capurso G, Bueno-de-Mesquita HB, Werner J, Gazouli M, Butterbach K, Ivanauskas A, Giese N, Petersen GM, Fogar P, Wang Z, Bassi C, Ryska M, Theodoropoulos GE, Kooperberg C, Li D, Greenhalf W, Pasquali C, Hackert T, Fuchs CS, Mohelnikova-Duchonova B, Sperti C, Funel N, Dieffenbach AK, Wareham NJ, Buring J, Holcátová I, Costello E, Zambon CF, Kupcinskas J, Risch HA, Kraft P, Bracci PM, Pezzilli R, Olson SH, Sesso HD, Hartge P, Strobel O, Małecka-Panas E, Visvanathan K, Arslan AA, Pedrazzoli S, Souček P, Gioffreda D, Key TJ, Talar-Wojnarowska R, Scarpa A, Mambrini A, Jacobs EJ, Jamroziak K, Klein A, Tavano F, Bambi F, Landi S, Austin MA, Vodickova L, Brenner H, Chanock SJ, Delle Fave G, Piepoli A, Cantore M, Zheng W, Wolpin BM, Amundadottir LT, Canzian F. The TERT gene harbors multiple variants associated with pancreatic cancer susceptibility. Int J Cancer. 2015; 137(9):2175-2183.

Václavíková R, Hughes DJ, Souček P. Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease. Gene. 2015;571(1):1-8.

Vymetalkova V, Soucek P, Kunicka T, Jiraskova K, Brynychova V, Pardini B, Novosadova V, Polivkova Z, Kubackova K, Kozevnikovova R, Ambrus M, Vodickova L, Naccarati A, Vodicka P. Genotype and Haplotype Analyses of TP53 Gene in Breast Cancer Patients: Association with Risk and Clinical Outcomes. PLoS One. 2015;10(7):e0134463.

Boušová I, Skálová L, Souček P, Matoušková P. The modulation of carbonyl reductase 1 by polyphenols. Drug Metab Rev. 2015; 29:1-14.

Havranek O, Kleiblova P, Hojny J, Lhota F, Soucek P, Trneny M, Kleibl Z. Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma. PLoS One. 2015;10(10):e0140819.

Soucek P, Xenobiotics, In: Encyclopedia of Cancer, Schwab, M (Ed.), 3rd ed., 2015, Springer Verlag.

Hodek P, Hrdinova J, Macova I, Soucek P, Mrizova I, Burdova K, Kizek R, Hudecek J, Stiborova M. Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450. Neuroendocrinol Lett. 2015;36 Suppl 1:38-45.

Václavíková R, Elsnerová K, Mohelníková-Duchoňová B, Bartáková A, Rob L, Škapa P, Hruda M, Bouda J, Vodička P, Souček P. Markery progrese a vzniku metastáz u ovariálního karcinomu sledované na základě genových expresních profilů. Plzen Lék Sborn 2015;81:39–55.

 

vydané v roce 2013:

Ehrlichova M, Mohelnikova-Duchonova B, Hrdy J, Brynychova V, Mrhalova M, Kodet R, Rob L, Pluta M, Gut I, Soucek P, Vaclavikova R. The association of taxane resistance genes with the clinical course of ovarian carcinoma. Genomics. 2013 Mar 28. [Epub ahead of print]

Kubrycht J, Sigler K, Soucek P, Hudecek J. Structures composing protein domains. Biochimie. 2013 Apr 10. [Epub ahead of print]

Campa D, Rizzato C, Capurso G, Giese N, Funel N, Greenhalf W, Soucek P, Gazouli M, Pezzilli R, Pasquali C, Talar-Wojnarowska R, Cantore M, Andriulli A, Scarpa A, Jamroziak K, Fave GD, Costello E, Khaw KT, Heller A, Key TJ, Theodoropoulos G, Malecka-Panas E, Mambrini A, Bambi F, Landi S, Pedrazzoli S, Bassi C, Pacetti P, Piepoli A, Tavano F, di Sebastiano P, Vodickova L, Basso D, Plebani M, Fogar P, Büchler MW, Bugert P, Vodicka P, Boggi U, Neoptolemos JP, Werner J, Canzian F. Genetic susceptibility to pancreatic cancer and its functional characterisation: The PANcreatic Disease ReseArch (PANDoRA) consortium. Dig Liver Dis. 2013; 45(2):95-9.

Brynychová V, Hlaváč V, Ehrlichová M, Václavíková R, Pecha V, Trnková M, Wald M, Mrhalová M, Kubáčková K, Pikus T, Kodet R, Kovář J, Souček P. Importance of transcript levels of caspase-2 isoforms S and L for breast carcinoma progression. Future Oncology 2013; 9(3):427-38.

Campa D, Rizzato C, Bauer AS, Werner J, Capurso G, Costello E, Talar-Wojnarowska R, Jamroziak K, Pezzilli R, Gazouli M, Khaw KT, Key TJ, Bambi F, Mohelnikova-Duchonova B, Heller A, Landi S, Vodickova L, Theodoropoulos G, Bugert P, Vodicka P, Hoheisel J, Delle Fave G, Neoptolemos J, Soucek P, Buchler MW, Giese NA, Canzian F. Lack of replication of seven pancreatic cancer susceptibility loci identified in two Asian populations. Cancer Epidemiol Biomarkers Prev. 2013; 22(2):320-3.

Mohelnikova-Duchonova B, Brynychova V, Oliverius M, Honsova E, Kala Z, Muckova K, Soucek P. Differences in transcript levels of ABC transporters between pancreatic adenocarcinoma and non-neoplastic tissues. Pancreas 2013; 42(4):707-16.

Nilsson R, Antić R, Berni A, Dallner G, Dettbarn G, Gromadzinska J, Joksić G, Lundin C, Palitti F, Prochazka G, Rydzynski K, Segerbäck D, Souček P, Tekle M, Seidel A. Exposure to polycyclic aromatic hydrocarbons in women from Poland, Serbia and Italy - relation between PAH metabolite excretion, DNA damage, diet and genotype (the EU DIEPHY project). Biomarkers. 2013;18(2):165-73.

Hlaváč V, Brynychová V, Václavíková R, Ehrlichová M, Vrána D, Pecha V, Koževnikovová R, Trnková M, Gatěk J, Kopperová D, Gut I, Souček P. The expression profile of ABC transporter genes in breast carcinoma. Pharmacogenomics 2013; 14(5):515-29.

Rizzato C, Campa D, Pezzilli R, Soucek P, Greenhalf W, Capurso G, Talar-Wojnarowska R, Heller A, Jamroziak K, Khaw KT, Key TJ, Bambi F, Landi S, Mohelnikova-Duchonova B, Vodickova L, Büchler MW, Bugert P, Vodicka P, Neoptolemos JP, Werner J, Hoheisel JD, Bauer AS, Giese N, Canzian F. ABO blood groups and pancreatic cancer risk and survival: Results from the PANcreatic Disease ReseArch (PANDoRA) consortium. Oncol Rep. 2013;29(4):1637-44.

 

vydané v roce 2012:

Hubackova M, Vaclavikova R, Ehrlichova M, Mrhalova, Kodet R, Kubackova K, Vrána D, Gut I, Soucek P. Association of superoxide dismutases and NAD(P)H oxidoreductases with prognosis of patients with breast carcinomas. Int J Cancer 2012;130(2):338-348.

Hlavata I, Mohelnikova-Duchonova B, Vaclavikova R, Liska V, Pitule P, Novak P, Bruha J, Vycital O, Holubec L, Treska V, Vodicka, P, Soucek P. The role of ABC transporters in progression and clinical outcome of colorectal cancer. Mutagenesis 2012;27(2):187-96.

Houlston RS; members of COGENT. COGENT (COlorectal cancer GENeTics) revisited. Mutagenesis 2012;27(2):143-51. IF = 3.500

Mohelnikova-Duchonova B, Oliverius M, Honsova E, Soucek P. Evaluation of reference genes and normalization strategy for quantitative real-time PCR in human pancreatic carcinoma. Dis Markers 2012;32(3):203-10.

Otová B, Ojima I, Václavíková R, Hrdý J, Ehrlichová M, Souček P, Vobořilová J, Němcová V, Zanardi I, Horský S, Kovář J, Gut I. Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes. Invest New Drugs. 2012; 30:991–1002.

Kubrycht J, Sigler K, Souček P. Virtual interactomics of proteins from biochemical standpoint. Mol Biol Int. 2012;2012:976385.

Ehrlichová M, Ojima I, Chen J, Václavíková R, Němcová-Fürstová V, Vobořilová J, Simek P, Horský S, Souček P, Kovář J, Brabec M, Gut I. Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ADR-RES cells. Naunyn Schmiedebergs Arch Pharmacol. 2012;385(10):1035-48.

Lo WS, Lim YP, Chen CC, Hsu CC, Souček P, Yun CH, Xie W, Ueng YF. A dual function of the furanocoumarin chalepensin in inhibiting Cyp2a and inducing Cyp2b in mice: the protein stabilization and receptor-mediated activation. Arch Toxicol. 2012; 86(12):1927-38.

Vaclavikova R, Ehrlichova M, Hlavata I, Pecha V, Kozevnikovova R, Trnkova M, Adámek J, Edvardsen H, Kristensen VN, Gut I and Soucek P. Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis. Clin Chem Lab Med 2012;50(11):1999–2007.

Slyskova J, Korenkova V, Collins AR, Prochazka P, Vodickova L, Svec J, Lipska L, Levy M, Schneiderova M, Liska V, Holubec L, Kumar R, Soucek P, Naccarati A, Vodicka P. Functional, genetic and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas. Clin Cancer Res. 2012; 18(21):5878-5887.

 

vydané v roce 2011:

Hanova M, Vodickova L, Vaclavikova R, Smerhovsky Z, Stetina R, Hlavac P, Naccarati A, Slyskova J, Polakova V, Soucek P, Kumar R, Hemminki K, Vodicka P. DNA damage, DNA repair rates and mRNA expression levels of cell cycle genes (TP53, p21CDKN1A, BCL2 and BAX) with respect to occupational exposure to styrene. Carcinogenesis 2011;32(1):74-9.

Mohelnikova-Duchonova B, Marsakova L, Vrana D, Holcatova I, Ryska M, Smerhovsky Z, Slamova A, Schejbalova M, Soucek P. Superoxide Dismutase and NAD(P)H Quinone Oxidoreductase Polymorphisms and Pancreatic Cancer Risk. Pancreas 2011;40(1):72-78.

Soucek P, Kondrova E, Hermanek J, Stopka P, Boumendjel A, Ueng YF, Gut I. New model system for testing effects of flavonoids on doxorubicin-related formation of hydroxyl radicals. Anti-cancer Drugs 2011;22(2):176-84.

Hughes D, Hlavatá I, Soucek P, Pardini B, Naccarati A, Vodickova L, O'Morain C, Vodicka P. Ornithine Decarboxylase G316A Genotype and Colorectal Cancer Risk. Colorectal Dis 2011;13(8):860-4.

Hughes DJ, Hlavatá I, Soucek P, Pardini B, Naccarati A, Vodickova L, Jenab M, O’Morain C, and Vodicka P. Variation in the Vitamin D receptor gene is not associated with Colorectal Cancer in the Czech Republic. Journal of Gastrointestinal Cancer 2011;42(3):149-54.

Ueng YF, Chen CC, Chung YT, Liu TY, Chang YP, Lo WS, Murayama N, Yamazaki H, Souček P, Chau GY, Chi CW, Chen RM, Li DT. Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo. Br J Pharmacol 2011;163(6):1250-62.

Havranek O, Spacek M, Hubacek P, Mocikova H, Benesova K, Soucek P, Trneny M, Kleibl Z. No association between the TP53 codon 72 polymorphism and risk or prognosis of Hodgkin and non-Hodgkin lymphoma. Leuk Res 2011;35(8):1117-9.

Mohelnikova-Duchonova B, Soucek P, The Role of Membrane Transporters in Cellular Resistance of Pancreatic Carcinoma to Gemcitabine and Erlotinib. In: Horizons in Cancer Research, Volume 46, (Hiroto S. Watanabe ed.), NOVA Science Publishers Inc., NY, USA, 2011.

vydané v roce 2010:

Vrana D, Novotny J, Holcatova I, Hlavata I, Soucek P. CYP1B1 gene polymorphism modifies pancreatic cancer risk but not survival. Neoplasma 2010;57(1):15-9.

Mohelnikova-Duchonova B, Vrana D, Holcatova I, Ryska M, Smerhovsky Z, Soucek P. CYP2A13, ADH1B and ADH1C Gene Polymorphisms and Pancreatic Cancer Risk. Pancreas, 2010;39(2):144-148.

Chou YC, Chung YT, Liu TY, Wang SY, Chau GY, Chi CW, Soucek P, Krausz KW, Gelboin HV, Lee CH, Ueng YF. The oxidative metabolism of dimemorfan by human cytochrome P450 enzymes. J Pharmacol Sci, 2010; 99(2):1063-77.

Naccarati A, Pardini B, Polakova V, Smerhovsky Z, Vodickova L, Soucek P, Vrana D, Holcatova I, Ryska M, Vodicka P. Genotype and haplotype analysis of TP53 gene and the risk of pancreatic cancer: an association study in the Czech Republic. Carcinogenesis 2010;31(4):666-70.

Mateju M, Stribrna J, Zikan M, Kleibl Z, Janatova M, Kormunda S, Novotny J, Soucek P, Petruzelka L, Pohlreich P. Population-based study of BRCA1/2 mutations: Family history based criteria identify minority of mutation carriers. Neoplasma 2010;57(3):280-5.

Méplan C, Hughes DJ, Pardini B, Naccarati A, Soucek P, Vodickova L, Hlavatá I, Vrána D, Vodicka P, Hesketh JE. Genetic variants in selenoprotein genes increase risk of colorectal cancer. Carcinogenesis 2010;31(6):1074-9.

Soucek P, Susova S, Mohelnikova-Duchonova B, Gromadzinska J, Morawiec-Sztandera A, Vodicka P, Vodickova L Polymorphisms in xenobiotic-metabolizing enzymes and the risk of head and neck squamous cell carcinoma in the Slavic population of the central Europe. Neoplasma 2010;57(5):415-21.

Hlavata I, Vrana D, Smerhovsky Z, Pardini B, Naccarati B, Vodicka P, Novotny J, Mohelnikova-Duchonova B, Soucek P. Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1, and GSTT1 and risk of colorectal cancer in a Czech population. Oncol Rep, 2010; 24(5):1347-53.

Mohelnikova-Duchonova B, Havranek O, Hlavata I, Foretova L, Kleibl Z, Pohlreich P, Soucek P. CHEK2 gene alterations in the forkhead-associated domain, 1100delC and del5395 do not modify the risk of sporadic pancreatic cancer. Cancer Epidemiology, 2010;34(5):656-658.

Hanova M, Stetina R, Vodickova L, Vaclavikova R, Hlavac P, Smerhovsky Z, Naccarati A, Polakova V, Soucek P, Kuricova M, Manini P, Kumar R, Hemminki K, Vodicka P. Modulation of DNA repair capacity and mRNA expression levels of XRCC1, hOGG1 and XPC genes in styrene-exposed workers. Toxicol Appl Pharmacol, 2010;248(3):194-200.

Mohelníková-Duchoňová B, Souček P. Role membránových transportérů v chemorezistenci karcinomu pankreatu při terapii gemcitabinem. Klin Onkol. 2010;23(5):306-10. Review, in Czech.

Souček P: Význam genetických polymorfismů enzymů metabolizujících léčiva u nádorových onemocnění. In: Metabolismus léčiv a jiných xenobiotik (Ed. Skálová L. a kolektiv), vydalo Karolinum v Praze 2010, s.116-122, Monography in Czech.

 

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